Well, I got the speaker upgrade sorted out!
Ended up getting Focal AS165 Components, Pioneer GM-D1004 Amp and took my Alpine SWE-815 8" sub out from my other car. Remarkable sound quality and bass now, ridiculously loud too!
The CT25TY06 do not fit the Focals unfortunately, luckily the ones from the Pioneer speakers I had fitted perfectly.
Applied sound deadening to the inside of both doors, foam tape between speaker and speaker mount, foam tape between speaker mount and door, cloth tape over all trim clips on the door card too. I used speaker adapters to retain the factory wiring.
Amp wired in via a Toyota ISO connector to retain the factory wiring, got the speaker crossovers in the doors and fitted the tweeters on the upper door trim (this was easier than running wires through the door shuts, meaning connecting the crossovers was much easier and it looks nice too), I didn't want to still use the factory tweeters in dash though. Also speaker wire adapters for the factory tweeters seem hard to come by, as NONE of the speakers work when the factory tweeters are disconnected (worth remembering) I made brideging cables instead. I had to shave off about 0.5mm off the smallest spade connectors on the bench grinder to make them fit (held connectors with pliers).
Sub power connected via rear speaker wiring on the ISO connector, power taken from permanent live under bonnet (not battery, I don't like the idea of connecting straight to the battery), earth connected near the front seat belt anchor under the interior trim. Sub remote wire hidden and remote (gain & phase control etc) sits in front of the cup holders neatly in the cubby hole, next to the Amazon Echo Auto, so everything is voice controlled (phone Sat Nav, music player & phone calls etc), I have my phone on a cup holder phone holder.
Sounds absolutely fantastic, absolutely blown away with it to be honest. Fair bit of work but a nice neat install, nothing looks out of place and no factor wires butchered! Very happy, the advice is appreciated 😊